Myasthenia gravis Lambert–Eaton overlap syndrome: Recommended modification for the diagnostic criteria

Shin J. Oh MD

In 2016, MLOS (myasthenia gravis Lambert–Eaton overlap syndrome) was coined to represent an entity of overlap syndrome of myasthenia gravis and Lambert–Eaton myasthenic syndrome. Fifty-five MLOS patients have been identified. Modification of the diagnostic criteria for MG by adding MuSK positive antibody testing is recommended. Two MuSK positive MLOS patients were identified by the new diagnostic criteria.

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